Those caught driving under the influence of alcohol and/or drugs will be arrested.
"As people get together to celebrate the holiday weekend, it is important that they remain responsible behind the wheel," said OTS Director Christopher J. Murphy. "Driving under the influence is extremely dangerous. California is increasing enforcement during the holiday to ensure that those who choose to drive while impaired will be caught and arrested."
Statistics show that, on average, two people die every day in California in an impaired driving collision, and many times that are seriously injured.
The CHP, Avoid DUI Task Forces and more than 115 local police departments across the state will be setting up DUI checkpoints and saturation patrols to deter potential impaired drivers and take those under the influence off the road.
In 2011, 774 California drivers with a blood alcohol content of .08 or higher were killed in alcohol-impaired crashes.
A first-time DUI conviction can cost up to $10,000 in fines, legal fees, and insurance increases.